21 Jan: “–extract assortment” and “–ban diversity” no more mistake away when its input files have an effective chromosome password absent on the newest dataset.
: Fixed –meta-analysis-se-industry bug. –meta-analysis-chr-field and –meta-analysis-bp-field flags added. On creativity create, –dfam consistently mistakes aside which have a suitable content, rather than possibly segfaulting, whenever zero good circumstances are present.
28 October: –meta-analysis-se-profession banner extra, getting interoperation which have latest PLINK 2.0 logistic regression output (which uses good ‘LOG(OR)_SE’ industry name so you’re able to disambiguate the quality error’s gadgets).
Fixed “–model gen” permutation testing bug
twenty-four October: Fixed uninitialized-adjustable insect for the –serving + –q-score-assortment. “–indep-pairwise 500kb . ” functions securely once again (the previous generate expected a space up until the ‘kb’).
cuatro Mar: Supports during the demand-range help text are now found in a way much more similar to many other tools. –screening now really works properly whenever a good numeric conflict was step 1 earlier in the day the end.
twenty six May (beta 6): –merge-equal-pos bugfixes. For those who utilized –merge-equal-pos that have .bed+.bim+.fam filesets in which allele acquisition might have differed between .bim data files, otherwise that have one .ped+.chart fileset whatsoever, i encourage redoing that run.
: –meta-analysis ‘report-all’ today profile unique statistics unlike ‘NA’ when N=step 1. Fixed an enthusiastic inaccuracy during the –adjust’s management of really small p-philosophy. –make-just-fam works securely with just .fam type in once again.
14 Late (beta 5): –file + –merge[-list] bugfix. map file try unsorted, but if you have the possibility we recommend redoing people –document + –blend and you may –document + –merge-listing kostenlose asiatische Dating-Seiten ohne Bezahlung multiple-.ped merges performed which have prior to plink 1.9 generates. (.bed combining are unchanged, and you can –merge-listing rather than –file are around never influenced.)
fifteen October: A2 allele is starting to become constantly source on chr3 within a lot of Genomes phase 1 packages. As a general rule, you should not anticipate to keep REF/ALT alleles straight that have PLINK 1.x, but we tried to build A2 constantly site within these data files whilst still being didn’t somewhat allow; sorry about this. (As to the reasons try this found today, more dos.five years following the fact? As the PLINK dos.0 is now offering good –ref-from-fa flag that may with ease look for these mistake.)
13 Oct: “–freq counts” don’t gives reversed results when alleles was turned out of the initial .bim/.sleep acquisition. Repaired –logistic bug that’ll result in spurious NA efficiency.
seven October: Repaired part-situation (a couple of four haplotypes haven’t any understood observations) bug when you look at the –ld/–r2/–blocks/–clump’s mathematical phasing process. 32-part create are now able to kinds >2GB .bed files in place of crashing. –annotate and you can –gene-statement today work with –allow-extra-chr.
15 Aug: –lasso will be today work properly whenever there are trials with covariates introduce although chief phenotype destroyed.
21 May: “–linear communications gender” and you may “–logistic communications sex” today work effectively when zero covariates are present. –tucc added to invention create.
20 March (beta cuatro): –pca var-wts today accounts allele requirements. Minor statistical phasing bugfix. –[max-]mac computer, –Roentgen, and you will –thin-indiv[-count] no more classified since unpredictable. PLINK 2.0 alpha stimulates are now readily available.
Which bug is inclined to help you produce when your very first
13 November: –geno/–destroyed now beat heterozygous haploid calls since nonmissing; this can be in keeping with –brain, and you may PLINK step 1.07’s decisions that have –recode/–make-sleep active. They’ve been now inconsistent in what PLINK step one.07 did as opposed to –recode/–make-bed; play with –make-sleep + –set-hh-destroyed first if you need the outdated behavior. “–ci 0.95” no more provides ‘L94’/’U94’ column brands whenever plink gets unlucky having rounding. Small –exclude/–extract/–flip bugfix getting input files no newline towards the bottom. –qfam[-within] bugfix. –dosage ‘sex’ modifier today performs securely when certain products was basically filtered aside (age.g. just like the specific phenotypes have been lost).
20 September: VCF export no further removes an alt allele absent regarding the immediate dataset, because of a retroactive up-date to the VCF specs.